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Molecular characterization of Streptococcus suis isolates recovered from Ontario nursery pigs between 2013 and 2018

Picture of Vahab Farzan
Vahab Farzan

University of Guelph

Project Start: Mar 2019
Project Completion: Jul 2022

This study revealed that host genetics, tonsil microbiome, and farm factors influence S. suis disease development, while diverse antimicrobial resistance genes found in healthy pigs suggest a reservoir that could transfer resistance to pathogenic S. suis strains.

Molecular characterization of Streptococcus suis isolates recovered from Ontario nursery pigs between 2013 and 2018: Towards development of an effective vaccine

The wide distribution of virulence associated factor genes in S. suis isolates suggests that host factors such as tonsil microbiome, and pig genetic markers as well as different farm related factors may contribute to S. suis disease development.  In addition, the diversity of mobile genetic elements carrying antimicrobial resistance (AMR) genes in S. Suis isolates from healthy pigs indicates a potential reservoir of AMR genes to pathogenic S. suis in swine. The results of this study contribute to understanding the pathogenesis of S. suis and its control efforts.

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